6533b85afe1ef96bd12b988d
RESEARCH PRODUCT
Prognostic value of IL-6 and IL-10 serum levels and immunonutritional assessment in determining postoperative complications after geriatric surgery
G DianaGiovanni GuercioFrancesco BavettaBianca CudiaBalistrericarmela RitaCalogero Ricottasubject
Settore MED/04 - Patologia GeneralePathologymedicine.medical_specialtybiologypre- and postoperative profile of some inflammatory markersbusiness.industryLymphocyteSerum albuminInterleukinGastroenterologySettore MED/18 - Chirurgia GeneraleInterleukin 10medicine.anatomical_structureInternal medicineMeeting Abstractmedicinebiology.proteinGeriatric surgeryInterleukin productionGeriatrics and GerontologyInterleukin 6Complicationbusinessdescription
The onset of postoperative septic complications has recently been associated to serum levels of interleukin (IL) IL-6 and IL-10. Patients with complications have higher serum levels than patients without complication after surgery. IL-6 has been recognized as early marker of postoperative septic events. Furthermore IL-6 increases with age, expecially if there are associated diseases. It is a sign of functional deterioration of different organs. The disregulation in interleukin production, anesthetic drugs, hemorrhage and transfusions may lead to the onset of postoperative complications. The latter are more frequent in oncologic patients. The aim of our study is to evaluate pre- and postoperative profile of some inflammatory markers (IL-6, IL-10 and Creactive protein CRP) and immunonutritional assessment (through albumin serum levels and lymphocyte count) in a group of elderly patients undergone to major intrabdominal surgery. We related the data obtained to the onset of postoperative complications.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2009-04-01 | BMC Geriatrics |