6533b85afe1ef96bd12b9c94

RESEARCH PRODUCT

Brain lateralization probed by water diffusion at the atomic to micrometric scale

F. NataliC. DolceJ. PetersC. StellettaB. DeméJ. OllivierG. LeducA. CupaneE.l. Barbier

subject

[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imagingbrain[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiologylcsh:MedicineFacilitated DiffusionArticleCerebellumScattering Small AngleAnimalslcsh:ScienceDominance CerebralCerebrumMyelin SheathQuantitative Biology::Neurons and Cognitionneutron scatteringlcsh:RWaterwater diffusionMolecular biophysicsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)neutron scattering diffusion nuclear magnetic resonance water dynamicsNeutron DiffractionDiffusion Magnetic Resonance Imaginglcsh:QCattleAstrophysics::Earth and Planetary AstrophysicsBiological physics

description

International audience; Combined neutron scattering and diffusion nuclear magnetic resonance experiments have been used to reveal significant interregional asymmetries (lateralization) in bovine brain hemispheres in terms of myelin arrangement and water dynamics at micron to atomic scales. Thicker myelin sheaths were found in the left hemisphere using neutron diffraction. 4.7 T dMRI and quasi-elastic neutron experiments highlighted significant differences in the properties of water dynamics in the two hemispheres. The results were interpreted in terms of hemisphere-dependent cellular composition (number of neurons, cell distribution, etc.) as well as specificity of neurological functions (such as preferential networking).

yearjournalcountryeditionlanguage
2019-04-17Scientific Reports
10.1038/s41598-019-51022-1http://dx.doi.org/10.1038/s41598-019-51022-1