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RESEARCH PRODUCT
Rapid microwave assisted hydrolysis of formetanate
ÁNgel Morales-rubioK. Dema-khalafM. De La Guardiasubject
Detection limitChromatographymedicine.diagnostic_testRelative standard deviationBiochemistryMicrowave assistedAnalytical Chemistrychemistry.chemical_compoundHydrolysischemistryFormetanateSpectrophotometrymedicineEnvironmental ChemistryTrace analysisDerivatizationSpectroscopydescription
Abstract A fast microwave-assisted hydrolysis procedure has been developed for the derivatization of formetanate previously to the flow-injection spectrophotometric determination of m -aminophenol by reaction with p -aminophenol. Formetanate is quantitatively hydrolyzed with 0.1 M NaOH in 150 s using a closed polyetrafluoroethylene reactor with 115 ml internal volume and a radiation power of 390 W. The above procedure has been applied, as a previous step, for the flow-injection spectrophotometric determination of formetanate in spiked water samples and accurate and precise results have been found. The method permits to obtain a limit of detection of 0.025 mg 1 −1 of formetanate. The relative standard deviation of five independent analyses of a simple containing 6 mg 1 −1 formetanate was 0.5%.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-09-01 | Analytica Chimica Acta |