6533b85afe1ef96bd12b9ed9
RESEARCH PRODUCT
Aceclofenac cream versus piroxicam cream in the treatment of patients with minor traumas and phlogistic affections of soft tissues: a double-blind study
Alberto BelluatiAldo PognaniLuigi TessariLuciano CecilianiGiovanni ThovezAlberto SiclariUmberto MartoranaGiuseppe LetiziaLuigi PagliaraLuigi P. SolimenoGaetano TorriEugenio Montullsubject
PharmacologyChemotherapymedicine.medical_specialtyRandomizationbusiness.industryVisual analogue scalemedicine.medical_treatmentSoft tissuePiroxicamSurgeryDouble blind studyAnesthesiaMedicineAceclofenacPharmacology (medical)businessAdverse effectmedicine.drugdescription
Abstract The efficacy and safety of aceclofenac 1.5% cream and piroxicam 1% cream in 220 patients with soft-tissue injuries were evaluated in a double-blind, randomized, multicenter, comparative, parallel-group trial. Patients were randomly assigned to each treatment group to receive therapy three times a day for 7 days. The primary outcome measure of pain was evaluated using a visual analog scale (VAS) at baseline, day 4, and day 7 of the study. Safety was assessed by recording any adverse events that occurred and by monitoring any hemato-biochemical alterations during the study. After days 4 and 7 of treatment, a significant improvement ( P P
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1995-07-01 | Current Therapeutic Research |