6533b85afe1ef96bd12b9f1f

RESEARCH PRODUCT

Agar-based phantoms for skin diagnostic imaging

Jānis SpigulisAnna MaslobojevaLaura DambiteIlona KuzminaUldis RubinsVanesa LukinsoneIlze Osina

subject

food.ingredientfoodMaterials sciencePhotonPath lengthScatteringMedical imagingAgarRGB color modelChromophoreAbsorption (electromagnetic radiation)Biomedical engineering

description

Agar-based skin phantoms with different thicknesses and hemoglobin concentration were evaluated for diagnostics of skin lesions by RGB imaging. Scattering properties of the phantoms were simulated using intralipid, absorption properties – using lyophilized powder of human hemoglobin. RGB images of phantoms were captured by self-developed laboratory made devices. The algorithm for calculation of chromophore concentrations are based on Beer-Lambert law and includes the photon path length evaluated from the measured photon-time-of-flight signals. Optical properties and chromophore concentration maps of phantoms obtained from RGB images were analyzed. The influence of chromophore concentration on scattering and absorption, photon path length and chromophore maps are discussed.

yearjournalcountryeditionlanguage
2020-04-02Tissue Optics and Photonics
https://doi.org/10.1117/12.2555674