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RESEARCH PRODUCT
Inter/intramolecular Cherenkov radiation energy transfer (CRET) from a fluorophore with a built-in radionuclide.
Richard A. DecréauBertrand CollinYann Bernhardsubject
RadionuclideBrightnessFluorophoreChemistryAstrophysics::High Energy Astrophysical PhenomenaPhysics::Medical PhysicsMetals and AlloysAnalytical chemistryGeneral ChemistryFluorescenceCatalysisPhysics::GeophysicsSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsPhysics::Popular Physicschemistry.chemical_compoundPhysics::Plasma PhysicsIntramolecular forceMaterials ChemistryCeramics and Composites[CHIM]Chemical Sciences[CHIM.OTHE]Chemical Sciences/OtherLuminescenceAbsorption (electromagnetic radiation)Cherenkov radiationdescription
The Cherenkov radiation (CR) from [(18)F]-FDG, [(177)Lu]-LuCl3 and [(90)Y]-YCl3 was detected and CR energy transfer (CRET) to several fluorophores was examined. Subsequent fluorescence emission was found to be a function of the position of absorption bands with respect to the CR peak, energy of emitted particles, radionuclide/fluorophore loading, and fluorophore brightness. A variant of the best fluorophore with a built-in radionuclide was synthesized to achieve inter- and intra-molecular CRET.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-04-01 | Chemical communications (Cambridge, England) |