6533b85bfe1ef96bd12bb485

RESEARCH PRODUCT

Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial.

Zaira SardellaStefania LarcanRoberta Di PeriDaniele La BarberaRoberta ChianettaRoberto CitarrellaGiuseppe Maniaci La Cascia CaterinaYuri MannellaManfredi RizzoValter D. LongoSimonetta MontanaMario G. MirisolaLaura FerraroAlessandra Giammanco

subject

AdultMalemedicine.medical_specialtyAdolescentmedia_common.quotation_subjectFunctional therapydepression fasting‐mimicking diet functional therapy psychotherapy outcome self‐esteemPilot Projectslaw.inventionYoung AdultArts and Humanities (miscellaneous)Randomized controlled trialQuality of lifelawSettore M-PSI/08 - Psicologia ClinicamedicineHumansSettore MED/25 - PsichiatriaDepression (differential diagnoses)media_commonDepressionPilot trialSelf-esteemFastingMiddle AgedPsychotherapyClinical PsychologyTreatment OutcomePhysical therapyFemalemedicine.symptomPsychologyBody mass indexDieting

description

Objective: This randomized controlled trial examined the efficacy of adding a fasting‐mimicking diet to a structured psychotherapy protocol for treating depression.Design: Of 20 patients with depression, 10 were randomly assigned to psychotherapy and dieting (i.e., experimental group) and the other 10 to psychotherapy only (i.e., control group). Patients in both groups received20 individual sessions of functional therapy along with nutrition consultation. Patients in the control group were instructed to maintain their usual daily diets. Results: Both treatments were effective in reducing depression as well as increasing self‐esteem and quality of life. The experimental group showed improved self‐esteem and psychological quality of life as well as a reduction in their mean body mass index, in comparison to the control group. Conclusions: The study revealed initial evidence of the efficacy of combining psychotherapy with a fasting‐mimicking diet to treat depression and its correlates

10.1002/jclp.22971https://pubmed.ncbi.nlm.nih.gov/32394438