6533b85bfe1ef96bd12bb757
RESEARCH PRODUCT
Complexes of Ni(II) and Cu(II) with ofloxacin. Crystal structure of a new Cu(II) ofloxacin complex.
Alfonso CastiñeirasJoaquín BorrásInmaculada RubioBenigno MacíasMaría V. Villasubject
OfloxacinInorganic chemistryAnti-Infective Agents UrinaryCrystal structureTriclinic crystal systemCrystallography X-RayBiochemistryMass SpectrometryCoordination complexlaw.inventionInorganic ChemistryTetragonal crystal systemAnti-Infective AgentslawNickelSpectroscopy Fourier Transform InfraredMoleculeCrystallizationElectron paramagnetic resonancechemistry.chemical_classificationMolecular StructureMagnetic susceptibilityCrystallographychemistryCrystallizationCopperdescription
Several coordination compounds formed between Ni(II) or Cu(II) with ofloxacin have been synthesised and characterised. According to elemental chemical analysis and FT-IR spectroscopy data, direct reaction of Ni(II) and Cu(II) salts with ofloxacin leads to formation of precipitates for which mass spectrometry demonstrates their polymeric nature. However, crystalline [Cu(oflo)2(H2O)].2H2O is formed if the reaction is carried out in the presence of ammonia. This complex crystallises in the triclinic system, space group P-1 with a=9.2887(12), b=11.2376(14), c=17.874(2) A, alpha=92.12(3), beta=95.39(3), gamma=91.71(3) degrees and Z=2. The local geometry around the Cu(II) ion is a slightly distorted square base pyramid. Electronic spectra, magnetic susceptibility measurements and EPR spectra of the synthesised complexes indicate a tetragonal environment.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-04-01 | Journal of inorganic biochemistry |