6533b85bfe1ef96bd12bb766

RESEARCH PRODUCT

Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer

Andris RomašovsViktorija MokrickaElina FrolovaAldis Puķītis

subject

medicine.medical_specialtyS syndromebusiness.industryBile duct030232 urology & nephrologyCase ReportGeneral Medicinemedicine.diseaseStauffer syndromelcsh:Diseases of the genitourinary system. Urologylcsh:RC870-923GastroenterologyBronchogenic carcinoma03 medical and health sciencesProstate cancer0302 clinical medicinemedicine.anatomical_structureCholestasis030220 oncology & carcinogenesisInternal medicinemedicineIn patientbusinessViral hepatitis

description

Cholestasis is a symptom that can be present in many conditions, such as bile duct obstruction by malignant mases, obstruction by gallstone, acute and chronic viral hepatitis, and autoimmune disorders, such as primary biliary and sclerosing cholangitis. Stauffer syndrome is a rare type of paraneoplastic syndrome that presents as cholestasis with absence of underlying disease. Classically Stauffer syndrome has been described in renal cell cancer patients. In literature cholestasis as manifestation of paraneoplastic syndrome has also been described in patients with prostate adenocarcinoma and pancreatic and bronchogenic carcinoma. Conclusions. Stauffer syndrome should be kept in mind in patients who present with cholestasis with no underlying cause. We advise to exclude any possible causes of cholestasis, for example, obstruction of bile duct.

10.1155/2019/9745301https://doaj.org/article/be2c8fbc0a994ff1a78a30d08b47c91f