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RESEARCH PRODUCT
Oral Manifestations of Wolf-Hirschhorn Syndrome: Genotype-Phenotype Correlation Analysis
Márcio Diniz-freitasPedro DizIsabel MauraCandela SerranoJacobo LimeresGuillermo MachucaJose Cruz Ruiz-villandiegoRaquel Blanco-lagoJulián NevadoJulián NevadoJavier Silvestre-rangilJoaquín De Novasubject
Candidate genePediatricsmedicine.medical_specialtyGenotypegenotypelcsh:MedicineOligodontiaDiseaseContiguous gene syndromeOdontologiaArticle03 medical and health sciencesEpilepsy0302 clinical medicineGenotypemedicineOral manifestationsWolf–Hirschhorn syndrome0303 health sciencesWolf-Hirschhorn syndromebusiness.industry030305 genetics & hereditylcsh:RGeneral MedicineStomatognathic diseasesmedicine.disease4p-Patologiaoral manifestationsstomatognathic diseasesbusiness030217 neurology & neurosurgeryRare diseasestomatognathic diseasesdescription
Background: Wolf-Hirschhorn syndrome (WHS) is a rare disease caused by deletion in the distal moiety of the short arm of chromosome 4. The objectives of this study were to report the most representative oral findings of WHS, relate them with other clinical characteristics of the disease, and establish possible phenotype-genotype correlation. Methods: The study was conducted at 6 reference centers distributed throughout Spain during 2018&ndash
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-11-01 | Journal of Clinical Medicine |