6533b85cfe1ef96bd12bc117
RESEARCH PRODUCT
Successful treatment of a young patient with locally advanced clear cell adenocarcinoma of the uterine cervix undergoing chemoradiation followed by radical surgery
Vito ChianteraGabriella FerrandinaAlessio G. MorgantiAlessandro LucidiArnaldo CarboneM. De NinnoGabriella Macchiasubject
Adultmedicine.medical_specialtyAdvanced clear cell adenocarcinomaUterine Cervical NeoplasmRadical surgeryUterine Cervical NeoplasmsDisease-Free SurvivalObstetrics and gynaecologyadenocarcinoma uterine cervixUterine cervixmedicineHumansCombined Modality TherapyClear-cell adenocarcinomaRadical surgeryPathologicalSettore MED/08 - ANATOMIA PATOLOGICAbusiness.industryObstetrics and GynecologyMultimodal therapyChemoradiotherapy Adjuvantmedicine.diseaseMultimodal approachCombined Modality TherapyImmunohistochemistryMagnetic Resonance ImagingSurgeryChemoradiationReproductive MedicineAdenocarcinomaFemalebusinessChemoradiotherapyAdenocarcinoma Clear CellHumandescription
Clear cell adenocarcinoma (CCAC) of the uterine cervix is a rare variant of cervical adenocarcinoma accounting for approximately 4-9% of this disease. Given the rarity of this pathological entity, the optimal treatment management is far from being defined. Earlier evidence suggested that the prognosis of patients bearing cervical CCAC is worse than with other histotypes, thus making the investigation of multimodal treatment strategies clinically worthwhile. Herein, we report the first case of locally advanced, large size cervical CCAC in a young woman who was triaged to concomitant chemoradiotherapy followed by radical surgery and experienced a pathologically assessed optimal response to this multimodal approach. Copyright © 2013 S. Karger AG, Basel.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-01 |