AuX3-Mediated Selective Head-to-Head Dimerization of Difluoropropargyl Amides

6533b85cfe1ef96bd12bc157

RESEARCH PRODUCT

AuX3-Mediated Selective Head-to-Head Dimerization of Difluoropropargyl Amides

Carlos Del Pozo Santos Fustero Begona Fernandez Gerald B. Hammond Paula Bello

subject

Head to head Stereochemistry Chemistry medicine.drug_class Organic Chemistry medicine Chemical reduction Carboxamide Reactivity (chemistry)Selectivity Reductive elimination

description

A dimerization of difluoropropargyl amides by reaction with gold(III) halides is described. A reductive elimination of a divinylgold species can be invoked to rationalize its formation. Initial studies of the unusual reactivity of these 1,4-dihalo-1,3-dienes have been performed.

year	journal	country	edition	language
2009-09-18	The Journal of Organic Chemistry

https://doi.org/10.1021/jo9013436

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