6533b85cfe1ef96bd12bc808

RESEARCH PRODUCT

Existence and uniqueness results for a nonlinear evolution equation arising in growing cell populations

Ahmed ZeghalKhalid LatrachJesús Garcia-falset

subject

education.field_of_studyCell divisionDegree (graph theory)Applied MathematicsPopulationMathematical analysisNonlinear systemUniquenessBoundary value problemeducationNonlinear evolutionValue (mathematics)AnalysisMathematics

description

Abstract The present paper is concerned with a nonlinear initial–boundary value problem derived from a model introduced by Rotenberg (1983) describing the growth of a cell population. Each cell of this population is distinguished by two parameters: its degree of maturity μ and its maturation velocity v . At mitosis, the daughter cells and mother cells are related by a general reproduction rule. We prove existence and uniqueness results in the case where the total cross-section and the boundary conditions are depending on the total density of population. Local and nonlocal reproduction rules are discussed.

https://doi.org/10.1016/j.na.2013.11.027