6533b85cfe1ef96bd12bc8e7

RESEARCH PRODUCT

Fusion of biological membranes

Kirill KatsovMichael SchickMarcus Müller

subject

FusionMembraneMaterials scienceMonte Carlo methodGeneral Physics and AstronomyLipid bilayer fusionBiological membraneStatistical physicsBiological systemLeakage (electronics)

description

The process of membrane fusion has been examined by Monte Carlo simulation, and is found to be very different than the conventional picture. The differences in mechanism lead to several predictions, in particular that fusion is accompanied by transient leakage. This prediction has recently been verified. Self-consistent field theory is applied to examine the free energy barriers in the different scenarios.

https://doi.org/10.1007/bf02704174