6533b85cfe1ef96bd12bca1e

RESEARCH PRODUCT

Arboreasides A−E, Triterpene Saponins from the Bark of Cussonia arborea

Jean François MirjoletMarie Aleth Lacaille-duboisTomofumi MiyamotoBeibam Lucas SondengamOlivier DuchampGuy Beddos KouganGuy Beddos Kougan

subject

SaponinPharmaceutical SciencePharmacognosyAnalytical ChemistryTriterpeneDrug DiscoveryBotanyCameroonAraliaceaeNuclear Magnetic Resonance BiomolecularPharmacologychemistry.chemical_classificationMolecular StructurebiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidComplementary and alternative medicinechemistryvisual_artPlant Barkvisual_art.visual_art_mediumMolecular MedicineAraliaceaeBarkCussonia arborea

description

Five new triterpene saponins, arboreasides A-E (1-5), and two known saponins, ciwujianoside C(3) and 23-hydroxyursolic acid 28-O-alpha-L-rhamnopyranosyl-(1--4)-beta-D-glucopyranosyl-(1--6)-beta-D-glucopyranosyl ester, were isolated from the bark of Cussonia arborea. The structures were established using extensive 1D and 2D NMR spectroscopic analyses and mass spectrometry.

https://doi.org/10.1021/np8008094