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RESEARCH PRODUCT
Acute pancreatitis in children. An Italian multicentre study
Raffaele PezzilliAntonio Maria Morselli-labateAntonio CarroccioSalvatore CorraoV. LucidiL. Di PrimaE. CastellanoCristiana Barberasubject
Italy/epidemiologyMalemedicine.medical_specialtyAbdominal painURLSettore MED/09 - Medicina Internaacute pancreatitisBUNupper reference limitDiseasePancreatitis/epidemiologyGastroenterologyC-reactive proteinBiliary diseaseSettore MED/38 - Pediatria Generale E SpecialisticaInternal medicineMedicineHumansPancreatitis/etiologyChildblood urea nitrogenRetrospective StudiesPancreatic ducthuman immunodeficiency virusHepatologybiologybusiness.industryC-reactive proteinGastroenterologyHIVAcute Disease Child Female Humans Italy/epidemiology Male Pancreatitis/diagnosis Pancreatitis/epidemiology* Pancreatitis/etiology Retrospective Studiesacute pancreatitisBUN; blood urea nitrogen; CRP; C-reactive protein; HIV; human immunodeficiency virus; URL; upper reference limitmedicine.diseaseSurgerymedicine.anatomical_structureItalyPancreatitisAcute DiseaseEtiologybiology.proteinAcute pancreatitisPancreatitisFemalemedicine.symptomCRPbusinessPancreatitis/diagnosiHumandescription
Abstract Aim . To evaluate the clinical, morphological and aetiological aspects of acute pancreatitis in children in Italy. Patients . The hospital records of 50 consecutive patients with acute pancreatitis observed in 5 Italian Pediatric Departments were reviewed. Results . A total of 25 males and 25 females (median age 10.5 years, range 2–17) were studied. Of these patients, 48 (96%) had abdominal pain. The pancreatitis was associated with biliary disease in 10 patients (20%); it was due to viral infection in 6 patients (12%), pancreatic duct abnormalities in 4 (8%), familial chronic pancreatitis in 3 (6%), trauma in 5 (10%) and other causes in 5 (10%); the pancreatitis was of unknown origin in 17 patients (34%). Previous attacks of the disease had occurred in 14 patients. A diagnosis of mild pancreatitis was made in 41 patients (82%) and of severe disease in 9 (18%). One patient with severe pancreatitis died from multiorgan failure. Patients with severe pancreatitis had significantly higher serum concentrations of C-reactive protein than patients with mild pancreatitis. Hospital stay was similar for patients with the mild form and those with the severe form of the disease. Conclusions . In Italian children, acute pancreatitis is of unknown origin in about one-third of the children and is recurrent in 28% of the cases. The disease is severe in 18% of the cases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2002-05-01 |