6533b85cfe1ef96bd12bca4b

RESEARCH PRODUCT

Breakthrough in the α-Perchlorination of Acyl Chlorides

Federico ReverberiFrancesca D'annaAndrew F. ParsonsDomenico SpinelliVincenzo FrennaFranco GhelfiFranco BellesiaFulvia Felluga

subject

acid chlorideacyl chlorides halogenation chlorine base catalysisOrganic Chemistry2Halogenationchemistry.chemical_elementtetralkylammonium chlorideSettore CHIM/06 - Chimica Organicaacyl chloridesacid chloride perchlorination tetralkylammonium chlorideCatalysisAcylationacyl chlorides halogenation chlorine base catalysis 2; 2-dichloroacyl chlorideschemistry2-dichloroacyl chlorideshalogenationchlorineChlorineOrganic chemistryperchlorinationbase catalysis

description

The preparation of -perchloroacyl chlorides, from reaction of the corresponding unfunctionalized acyl halides with chlorine, was efficiently achieved under base-catalysis, using a tetraalkylammonium chloride as catalyst. The process is solvent-free and the procedure is easy, inexpensive, and suitable for scale-up.

yearjournalcountryeditionlanguage
2012-01-26
10.1055/s-0031-1289678http://hdl.handle.net/11368/2471329