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RESEARCH PRODUCT

Quantitative magnetic resonance imaging for focal liver lesions: bridging the gap between research and clinical practice

Roberto CannellaJules GregoryRiccardo SartorisValérie VilgrainValérie VilgrainLorenzo GarzelliMaxime RonotMaxime RonotMarco Dioguardi Burgio

subject

medicine.medical_specialtyQuantitative magnetic resonance imagingContrast MediaPerfusion scanningReview Article030218 nuclear medicine & medical imaging03 medical and health sciencesImaging Three-Dimensional0302 clinical medicineImage Interpretation Computer-AssistedmedicineHumansEffective diffusion coefficientRadiology Nuclear Medicine and imagingIn patientIntravoxel incoherent motionRadiomicsmedicine.diagnostic_testbusiness.industryLiver NeoplasmsMagnetic resonance imagingGeneral MedicinePerfusion imagingImage EnhancementPrognosisMagnetic Resonance ImagingClinical PracticeDiffusion Magnetic Resonance Imaging030220 oncology & carcinogenesisElasticity Imaging TechniquesDiffusion-weighted imagingRadiologyElastographyElastographySettore MED/36 - Diagnostica Per Immagini E Radioterapiabusiness

description

Magnetic resonance imaging (MRI) is highly important for the detection, characterization, and follow-up of focal liver lesions. Several quantitative MRI-based methods have been proposed in addition to qualitative imaging interpretation to improve the diagnostic work-up and prognostics in patients with focal liver lesions. This includes DWI with apparent diffusion coefficient measurements, intravoxel incoherent motion, perfusion imaging, MR elastography, and radiomics. Multiple research studies have reported promising results with quantitative MRI methods in various clinical settings. Nevertheless, applications in everyday clinical practice are limited. This review describes the basic principles of quantitative MRI-based techniques and discusses the main current applications and limitations for the assessment of focal liver lesions.

https://doi.org/10.1259/bjr.20210220