6533b85cfe1ef96bd12bcbb8
RESEARCH PRODUCT
Ménétrier's disease in a patient with refractory ulcerative colitis: a clinical challenge and review of the literature
Sofia RaoSofia RaoOmar KsissaOmar KsissaWalter FriesAnna Violasubject
AdultMalemedicine.medical_specialtymedicine.medical_treatmentGastroenterologyInflammatory bowel diseaseVedolizumabInternal medicineUstekinumabmedicineHumansGastritis HypertrophicColectomybusiness.industryGeneral Medicinemedicine.diseaseUlcerative colitisInfliximabInfliximabMénétrier's diseaseColitis UlcerativeUstekinumabbusinessRare diseasemedicine.drugdrugs: gastrointestinal system; gastroenterology; inflammatory bowel diseasedescription
Ménétrier’s disease (MD) is a rare disease of the stomach, characterised by hypertrophic gastric folds leading to protein loss. The association with ulcerative colitis (UC) is rare but has been reported in the literature. We report a case of a 29-year-old male affected by UC with an additional diagnosis of MD 3 years after UC diagnosis. UC was refractory to several treatment lines (thiopurines, infliximab, vedolizumab and ustekinumab), and the patient underwent colectomy. Octreotide was administered for MD normalising blood biochemistry, but it was not effective in inducing endoscopic remission of the stomach. Treatment options in patients with MD and UC are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2023-10-19 |