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RESEARCH PRODUCT
Aortic stiffness in patients with early sepsis
E StrīkeIndulis VanagsAndris GrabovskisSigita Kazunesubject
Aortamedicine.medical_specialtyPathologybusiness.industrySeptic shockInflammatory responseHemodynamicsCritical Care and Intensive Care Medicinemedicine.diseaseSepsismedicine.arteryInternal medicinePoster Presentationcardiovascular systemCardiologyMedicineAortic stiffnessIn patientbusinessPulse wave velocitydescription
Acute and chronic systemic inflammatory conditions are associated with aortic stiffening. Carotid-femoral pulse wave velocity (PWV), a marker of aortic stiffness, increases in patients with inflammatory diseases and independently correlates to levels of C-reactive protein (CRP). The effects of massive inflammatory response in early sepsis on mechanical properties of the aorta have not been investigated. The objective of the current study was to prospectively assess aortic stiffness in patients with early severe sepsis and septic shock and relate it to inflammatory and haemodynamic variables and outcome.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-03-01 | Critical Care |