6533b85cfe1ef96bd12bd3e0
RESEARCH PRODUCT
Chromosome painting of the pygmy tree shrew shows that no derived cytogenetic traits link primates and scandentia.
Marlys L. HouckSvetlana A. RomanenkoRoscoe StanyonPolina L. PerelmanFrancesca DumasF. Bigonisubject
Chromosome paintsMalePrimatesTupaiaZoologySettore BIO/08 - AntropologiaCell LineChromosome PaintingMolecular cytogeneticsTree shrewPhylogeneticsGeneticsAnimalsHumansTupaia minorMolecular BiologyGenetics (clinical)PhylogenyAncestral associations Molecular cytogeneticsPhylogeny TupaiabiologyTupaiidaebiology.organism_classificationChromosome BandingScandentiaKaryotypingChromosome paintingdescription
We hybridized human chromosome paints on metaphases of the pygmy tree shrew (<i>Tupaia minor</i>, Scandentia). The lack of the ancestral mammalian 4/8 association in both Primates and Scandentia was long considered a cytogenetic landmark that phylogenetically linked these mammalian orders. However, our results show that the association 4/8 is present in <i>Tupaia </i>along with not previously reported associations for 1/18 and 7/10. Altogether there are 11 syntenic associations of human chromosome segments in the pygmy tree shrew karyotype: 1/18, 2/21, 3/21, 4/8, 7/10, 7/16, 11/20, 12/22 (twice), 14/15 and 16/19. Our data remove any cytogenetic evidence that Scandentia has a preferential phylogenetic relationship with Primates.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-01-16 | Cytogenetic and genome research |