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RESEARCH PRODUCT

Asthma exacerbations and socio-economic status in French adults with persistent asthma: A prospective cohort study.

Katia MazalovicFlore JacoudAlexandra L DimaEric Van GanseMaeva NolinDidier CClaire ZabawaThe Astro-lab Group

subject

Pulmonary and Respiratory MedicineAdultHypersensitivity ImmediateMalePediatricsmedicine.medical_specialtyAdolescentGeneral PracticeComorbiditySeverity of Illness IndexBody Mass Index03 medical and health sciencesYoung Adult0302 clinical medicineImmunology and AllergyMedicineHumans030212 general & internal medicineSocial determinants of healthAnti-Asthmatic AgentsProspective StudiesProspective cohort studySocioeconomic statusAsthmaAsthma exacerbationsMedical Assistancebusiness.industrysocial sciencesmedicine.diseaseAsthma030228 respiratory systemSocioeconomic FactorsPediatrics Perinatology and Child HealthCohortpopulation characteristicsObservational studyFemaleFrancebusinessEmergency Service HospitalCohort study

description

Adults disadvantaged by poor socio-economic status (SES) are more severely affected by asthma compared to those with better SES. We aimed to determine whether the frequency of asthma exacerbations (AEx), as well as aspects related to AEx management, differed based on SES in patients treated with daily treatments.This study, part of the prospective observational cohort ASTRO-LAB, included French adult patients with persistent asthma. Patients were considered as low SES if they benefited from publicly funded special health insurance and/or were perceived as low SES by their general practitioner. AEx was defined as at least one of the following: asthma-related oral corticosteroid course, medical contact, hospitalization, and death. We examined associations between SES and AEx frequency, perceived triggering factors and type of medical contact after AEx.In our sample of 255 patients, 11.40% were considered as low SES. Patients with low SES did not report significantly more AEx than medium/high SES patients during one-year follow-up (0.79 versus 0.55, p = 0.38). The type of medical contact during AEx differed significantly between the two groups (p = 0.03): patients with medium/high SES consulted their general practitioner more frequently (OR = 2.23, 95% CI = 0.91-5.50, p = 0.08) and were less likely to visit an emergency department or be hospitalized (OR = 0.27, 95% CI = 0.09-0.84, p = 0.02).AEx frequency did not differ significantly between low and medium/high SES patients, but differences were found in the management of AEx. Studies are needed to better understand the relation between precariousness and management of asthma.

10.1080/02770903.2017.1391280https://pubmed.ncbi.nlm.nih.gov/29023163