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RESEARCH PRODUCT
ChemInform Abstract: Palladium-Catalyzed Domino C-H/N-H Functionalization: An Efficient Approach to Nitrogen-Bridged Heteroacenes.
Natsuyo KamimotoSeiji SugaSiegfried R. WaldvogelKoichi MitsudoDieter Schollmeyersubject
Indole testchemistry.chemical_compoundChemistryThiophenechemistry.chemical_elementMoietySurface modificationGeneral MedicineMedicinal chemistryNitrogenDominoCatalysisPalladiumdescription
Palladium-catalyzed domino CH/NH functionalization for the synthesis of novel nitrogen-bridged thienoacenes and 10H-benzo[4,5]thieno[3,2-b]indole derivatives from dihaloarene is reported. This domino sequence consists of initial CH functionalization of the benzo[b]thiophene moiety, followed by Buchwald–Hartwig coupling. This transformation is also useful for the synthesis of highly π-extended compounds.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-09-24 | ChemInform |