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RESEARCH PRODUCT
Echocardiographic reference ranges for normal left atrial function parameters results from the EACVI NORRE study
Sugimoto TadafumiRobinet SébastienDulgheru RalucaBernard AnneFederica IlardiContu LauraAddetia KarimaCaballero LuisKacharava GeorgeAthanassopoulos George DBarone DanieleBaroni MonicaCardim NunoHagendorff AndreasKrasimira HristovaLopez TeresaDe La Morena GonzaloBogdan A. PopescuPenicka MartinTolga OzyigitJose David Rodrigo CarboneroVan De Veire NicoVon Bardeleben Ralph StephanVinereanu DragosZamorano Jose LuisGo Yun YunMarchetta StellaNchimi AlainRosca MonicaCalin AndreeaMoonen MarieCimino SaraMagne JulienCosyns BernardGalli ElenaDonal ErwanHabib GilbertRoberta EspositoGalderisi MaurizioLuigi P. BadanoLang Roberto MLancellotti PatrizioAddetia Karimasubject
Maledeformation imagingPump functionEchocardiography Three-DimensionalSex Factor030204 cardiovascular system & hematologyCohort Studies0302 clinical medicineLeft atrialReference ValuesHealthy volunteersImage Processing Computer-AssistedAge Factoradult echocardiography; deformation imaging; left atrial function; reference values030212 general & internal medicineMultivariate AnalysiObserver VariationHealthy subjectsAge FactorsGeneral MedicineMiddle AgedReference StandardsHealthy VolunteerHealthy VolunteersHomogeneousRadiology Nuclear Medicine and imagingEchocardiographyCardiologyLinear ModelAtrial Function LeftFemale[SDV.IB]Life Sciences [q-bio]/BioengineeringCardiology and Cardiovascular MedicineHumanAdultmedicine.medical_specialtyadult echocardiographyStatistics Nonparametric03 medical and health sciencesSex FactorsInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingHeart AtriaLeft atrial functionbusiness.industryreference valueMED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLAREReference valuesMultivariate AnalysisLinear ModelsReference StandardParameterCohort StudieLarge groupbusinessdescription
International audience; Aims - To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group of healthy volunteers accounting for age and gender. Methods and results - A total of 371 (median age 45 years) healthy subjects were enrolled at 22 collaborating institutions collaborating in the Normal Reference Ranges for Echocardiography (NORRE) study of the European Association of Cardiovascular Imaging (EACVI). Left atrial data sets were analysed with a vendor-independent software (VIS) package allowing homogeneous measurements irrespective of the echocardiographic equipment used to acquire data sets. The lowest expected values of LA function were 26.1%, 48.7%, and 41.4% for left atrial strain (LAS), 2D left atrial emptying fraction (LAEF), and 3D LAEF (reservoir function); 7.7%, 24.2%, and -0.53/s for LAS-active, LAEF-active, and LA strain rate during LA contraction (SRa) (pump function) and 12.0% and 21.6% for LAS-passive and LAEF-passive (conduit function). Left atrial reservoir and conduit function were decreased with age while pump function was increased. All indices of reservoir function and all LA strains had no difference in both gender and vendor. However, inter-vendor differences were observed in LA SRa despite the use of VIS. Conclusion - The NORRE study provides contemporary, applicable echocardiographic reference ranges for LA function. Our data highlight the importance of age-specific reference values for LA functions.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-02-23 |