6533b85dfe1ef96bd12bdecd

RESEARCH PRODUCT

Haemodynamics of primary aldosteronism associated with adrenocortical adenoma: insights from bioimpedance cardiography measurements

Giulio GeraciGiuseppe MulèSantina CottoneCaterina Carollo

subject

Cardiac outputmedicine.medical_specialtybusiness.industryHemodynamicsHemodynamicsmedicine.diseaseEssential hypertensionAdrenal Cortex NeoplasmsAdrenocortical adenomaVascular StiffnessVascular stiffnessPrimary aldosteronismInternal medicineAdrenocortical AdenomaHyperaldosteronismInternal MedicinemedicineCardiologyHumansCardiac OutputEssential HypertensionAldosterone - Adrenocortical adenoma - Primary hyperaldosteronism . Hemodynamicsbusiness

description

In mid 1950s, Dr Jerome Conn described a patient with hypertension, and renal potassium wasting associated with adrenocortical adenoma and increased urinary excretion of a sodium-retaining hormone, initially termed electrocortin, which was subsequently shown to be aldosterone. This was the first full report of primary hyperaldosteronism associated with an aldosterone-producing adenoma (APA). It subsequently became apparent that similar abnormalities can occur in the absence of an adrenocortical tumor, and it is now recognized that the APA is just one of many subtypes of primary aldosteronism (PA).

https://doi.org/10.1111/joim.13127