6533b85dfe1ef96bd12bdf98
RESEARCH PRODUCT
Photochemically induced cross-links between DNA and alcohol dehydrogenase or salmine, respectively
B. TothK. Dosesubject
PhotochemistryBiophysicsAlcoholSalminechemistry.chemical_compoundPolydeoxyribonucleotidesCysteineProtaminesTyrosineGeneral Environmental ScienceAlcohol dehydrogenaseAlaninechemistry.chemical_classificationRadiationbiologyDNAGlutathioneAlcohol OxidoreductaseschemistryBiochemistryGlycineThiolbiology.proteinThymidineThymineThymidineCysteinedescription
Model experiments with two structurally different proteins (alcohol dehydrogenase and salmine) show that glycine, alanine, and tyrosine are by far more frequently involved in photochemically induced cross-link formations with DNA than is cysteine. The yields for cross-link formation of thymidine with salmine (cysteine-free) are about as high as those with alcohol dehydrogenase (a thiol protein).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1976-06-01 | Radiation and Environmental Biophysics |