6533b85dfe1ef96bd12be039
RESEARCH PRODUCT
Identification Of Mitotically Competent SOX2+ Cells In White Matter Of Normal Human Adult Brain
Angel Ayuso-sacidoJorge Oliver-de La CruzJosefa Carrión-navarroCarmen Escobedo-luceaJosé Manuel García-verdugoAntonio Gutierrez-martinsubject
education.field_of_studyPopulationSubventricular zoneBiologyIn vitroTemporal lobeCell biologyWhite mattermedicine.anatomical_structureSOX2nervous systemembryonic structuresmedicineGeneral Materials ScienceStem celleducationNeurosciencedescription
AbstractSOX2 expression is linked to the undifferentiated state of stem cells in mammalian neurogenic niches. While its expression has been reported in the adult human subventricular zone (SVZ), to date it has not been detected in adult human white matter. Here we describe a population of SOX2+ cells from the white matter of the adult human temporal lobe, which proliferate and express glial markers in vitro.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-08-16 |