6533b85dfe1ef96bd12bf07f

RESEARCH PRODUCT

YJL159w does encode Pir2/Hsp150

Jesús ZuecoIsmaïl Moukadiri

subject

GeneticsStrain (biology)BioengineeringBiologyENCODEApplied Microbiology and BiotechnologyBiochemistryYeastDivergencePolymorphism (computer science)GeneticsPeptide sequenceGeneBiotechnologySequence (medicine)

description

In this paper we compare the sequence of the gene HSP150/PIR2, independently determined by two different groups, with that present in the yeast database as YJL159w, determined within the Yeast Sequencing Project. Although YJL159w is believed to encode Hsp150/Pir2, there are important differences between the amino acid sequence coded by this ORF and that of HSP150/PIR2. To find out if this divergence is due to strain polymorphism or to a possible sequencing error, we have analysed the diverging zone of this ORF in three strains and have found it entirely consistent with the sequence reported as HSP150/PIR2, concluding that the divergence is probably due to a sequencing error in YJL159w. Copyright © 2000 John Wiley & Sons, Ltd.

https://doi.org/10.1002/1097-0061(20010315)18:4<323::aid-yea671>3.0.co;2-c