6533b85dfe1ef96bd12bf24f
RESEARCH PRODUCT
Risk of aortic dissection in patients with ascending aorta aneurysm: a new biological, morphological, and biomechanical network behind the aortic diameter
Laura AstaCalogera PisanoGiovanni RuvoloBalistrericarmela RitaMaria Sabrina FerranteClaudia AltieriPaolo NardiDario BuioniFabio BertoldoDaniele Trombettisubject
Aortic dissectionSettore MED/23business.industrymedicineIn patientAnatomyAscending aorta aneurysmAortic diameterCardiology and Cardiovascular Medicinemedicine.diseasebusinessAscending aorta aneurysm ascending aorta size aortic dissection genetic risk factors morphological aspects surgical indication for aortic repairdescription
Thoracic aortic aneurysm represents a deadly condition, particularly when it evolves into rupture and dissection. Proper surgical timing is the key to positively influencing the survival of patients with this pathology. According to the most recent guidelines, ascending aorta size ≥ 55 mm and a rate of growth ≥ 0.5 cm per year are the most important factors for surgical indication. Nevertheless, a lot of evidence show that aortic ruptures and dissections might occur also in small size ascending aorta. In this review, we sought to analyze a new biological and morphological network behind the aortic diameter that need to be considered in order to identify the portion of patients with thoracic aortic aneurysm who are at increased risk of aortic complications, despite current aortic guidelines not advising surgical intervention in this group
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-01-01 |