Impact of the post-treatment conditions of parent silica on the silanization of n-octadecyl bonded silica packings in reversed-phase high-performance liquid chromatography

6533b85efe1ef96bd12bf412

RESEARCH PRODUCT

Impact of the post-treatment conditions of parent silica on the silanization of n-octadecyl bonded silica packings in reversed-phase high-performance liquid chromatography

F Großmann K.k. Unger V Ehwald C. Du Fresne Von Hohenesche

subject

Chromatography Silica gel Organic Chemistry Reproducibility of Results Hydrochloric acid General Medicine Reversed-phase chromatography Silanes Mesoporous silica Hydroxylation Silicon Dioxide Biochemistry High-performance liquid chromatography Analytical Chemistry law.invention chemistry.chemical_compound Silanol chemistry law Silanization Calcination Chromatography High Pressure Liquid

description

Native mesoporous silica beads were subjected to a sequence of post-treatment procedure including hydrochloric acid treatment, calcination and subsequent rehydroxylation. The post-treated silica beads were converted into RP-18 silica by silanization with monochloro- and dimethoxy-n-octadecylsilanes, respectively. The influence of post-treatments and silanization conditions on the physico-chemical characteristics and on the chromatographic behaviour of the RP-silicas was studied. Also the changes of the pore structural parameters and the silanol group densities during the post-treatment and silanization were assessed.

year	journal	country	edition	language
2001-03-23	Journal of Chromatography A

https://doi.org/10.1016/s0021-9673(00)01194-8

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