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RESEARCH PRODUCT

Taurine and the Lung

Esteban J. MorcilloFrancesco SantangeloJulio Cortijo

subject

chemistry.chemical_compoundTaurineLungmedicine.anatomical_structureOzonechemistryParaquatmedicineNitrogen dioxidePharmacologyBleomycinProinflammatory cytokineEvans Blue

description

Taurine (TAU) is the most abundant free amino acid in many tissues and in particular in proinflammatory cells like polymorphonuclear leukocytes and tissues exposed to elevated levels of oxidants1. Furthermore, orally administered TAU has been reported to reduce lung oxidant damage from exposure to ozone, nitrogen dioxide, paraquat, amiodarone and bleomycin in animal models2–5.

https://doi.org/10.1007/978-1-4615-0077-3_49