6533b85efe1ef96bd12bfd9b

RESEARCH PRODUCT

Noncovalent force spectroscopy using wide-field optical and diamond-based magnetic imaging

Metin KayciMetin KayciDmitry BudkerDmitry BudkerShoujun XuSean LouretteLykourgos Bougas

subject

Materials sciencePhysics - Instrumentation and DetectorsMagnetometerFOS: Physical sciencesGeneral Physics and AstronomyApplied Physics (physics.app-ph)02 engineering and technologyengineering.material01 natural scienceslaw.inventionMagnetizationlaw0103 physical sciencesPhysics - Biological PhysicsSpectroscopyMassively parallelNanoscopic scale010302 applied physicsQuantum Physicsbusiness.industryForce spectroscopyDiamondInstrumentation and Detectors (physics.ins-det)Physics - Applied Physics021001 nanoscience & nanotechnology3. Good healthBiological Physics (physics.bio-ph)engineeringOptoelectronicsQuantum Physics (quant-ph)0210 nano-technologybusinessRealization (systems)

description

A realization of the force-induced remnant magnetization spectroscopy (FIRMS) technique of specific biomolecular binding is presented where detection is accomplished with wide-field optical and diamond-based magnetometry using an ensemble of nitrogen-vacancy (NV) color centers. The technique may be adapted for massively parallel screening of arrays of nanoscale samples.

10.1063/1.5125273http://arxiv.org/abs/1908.10052