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RESEARCH PRODUCT
Compromised Lung Volume and Hemostatic Abnormalities in COVID-19 Pneumonia: Results from an Observational Study on 510 Consecutive Patients
Ezio LanzaBarco StefanoStefano BarcoCorrado LodigianiMaria Elisa MancusoLuca BalzariniPierpaolo Di MiccoCostanza LisiPaola FerrazziGaia Messanasubject
medicine.medical_specialtySARS-CoV-2 pneumonia610 Medicine & health2700 General Medicine030204 cardiovascular system & hematologyLung injuryGastroenterologyArticlelung volume measurements03 medical and health sciences0302 clinical medicineInternal medicineD-dimerMedicineLung volumesCOVIDLungbusiness.industry10031 Clinic for AngiologyRCOVID-19General MedicineOdds ratiomedicine.diseasePneumoniamedicine.anatomical_structure030220 oncology & carcinogenesisHemostasisConcomitantD-dimerhemostasisMedicinebusinessdescription
Background: Hemostatic abnormalities have been described in COVID-19, and pulmonary microthrombosis was consistently found at autopsy with concomitant severe lung damage. Methods: This is a retrospective observational cross-sectional study including consecutive patients with COVID-19 pneumonia who underwent unenhanced chest CT upon admittance at the emergency room (ER) in one large academic hospital. QCT was used for the calculation of compromised lung volume (%CL). Clinical data were retrieved from patients’ files. Laboratory data were obtained upon presentation at the ER. Aim: The aim of this study was to evaluate the correlation between hemostatic abnormalities and lung involvement in patients affected by COVID-19 pneumonia as described using computer-aided quantitative evaluation of chest CT (quantitative CT (QCT)). Results: A total of 510 consecutive patients (68% males), aged 67 years in median, diagnosed with COVID-19 pneumonia, who underwent unenhanced CT scan upon admission to the ER, were included. In all, 115 patients had %CL >
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-06-29 |