6533b85efe1ef96bd12c079b
RESEARCH PRODUCT
A vinyl chloride-exposed worker with an adrenal gland angiosarcoma: a case report.
Maria Elena GianicoloEmilio Antonio Luca GianicoloEmilio Antonio Luca GianicoloMario CriscuoloMaurizio PortaluriJacqueline Valeriosubject
Malemedicine.medical_specialtyPathologyExtraepaticHealth Toxicology and Mutagenesismedicine.medical_treatmentAdrenal Gland NeoplasmHemangiosarcomaAdrenal Gland NeoplasmsVinyl ChlorideCase ReportOccupational ExposureMedicineNeoplasmHumansAngiosarcomaAdrenal Gland AngiosarcomaAgedChemotherapybusiness.industryPublic Health Environmental and Occupational HealthHepatic Angiosarcomamedicine.diseaseDermatology3. Good healthRadiation therapyOccupational DiseasesHemangiosarcomaAdrenal angiosarcomaCarcinogenslipids (amino acids peptides and proteins)businessdescription
Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1% of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and the pathologist. Data on the patient's occupational history was collected and analyzed. The bibliographic data was found on the PUBMED bibliographic search site after entering the word "extrahepaticangiosarcoma". We report a case of adrenal epithelioidangiosarcoma (AEA) in a 68 yr-old Caucasian male factory worker exposed to Vinyl Chloride (VC) for 15 yr. He underwent surgery, chemotherapy and radiotherapy. Hepatic angiosarcoma is a known consequence of VC exposure, but occupational causality of extra-hepatic angiosarcoma is controversial. Extra-hepatic angiosarcomas have been reported in VC workers, but never AEA. Cancerogenic effects of VC involve all endothelial areas of the body and extra-hepatic endothelial tumors may also be caused by this substance. This is the first published report of AEA diagnosed in a worker exposed to VC.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-12-03 | Industrial health |