6533b85ffe1ef96bd12c0f5f
RESEARCH PRODUCT
Polycondensed nitrogen heterocycles. Part17. Isoxazolo[4,3-d]pyrazolo[3,4-f][1,2,3]triazepine. A new ring system
Gaetano DattoloAnna Maria AlmericoEnrico AielloGirolamo CirrincioneGiuseppe Prestisubject
Organic Chemistrychemistry.chemical_elementNuclear magnetic resonance spectroscopyClostridium perfringensmedicine.disease_causeRing (chemistry)NitrogenCoupling reactionSalmonella cholerasuischemistry.chemical_compoundchemistryIntramolecular forceNitrationmedicineOrganic chemistrydescription
The title compounds were prepared by nitration of compounds 2, reduction of the dinitro derivatives 4 and diazotization of the diamino derivatives 6 followed by an intramolecular coupling reaction. Compound 4a showed good activity against Salmonella cholerasuis and Clostridium perfringens bacteria.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-09-01 | Journal of Heterocyclic Chemistry |