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RESEARCH PRODUCT
MALIGNANT TUMOR-LIKE GAASTRIC LESION DUE TO CANDIDA ALBICANS IN A DIABETIC PATIENT TREATED WITH CYCLOSPORIN: A CASE REPORT AND REVIEW OF THE LITERATURE
Giovanni TomaselloGiovam Battista RiniAurelio SeididaAngelo Maria PattiPisciotta GPasquale MansuetoAntonio CarroccioGaetana Di FedeDaniela CabibiAlberto D'alcamoDelia Sprinisubject
Pathologymedicine.medical_specialtyAntifungal AgentsSettore MED/09 - Medicina InternaSettore MED/08 - Anatomia PatologicaMalignancyGastroenterologyGeneral Biochemistry Genetics and Molecular BiologyCyclosporin aDiabetes mellitusInternal medicinePsoriasisCandida albicansCandidiasis Mycotic infection of the gastrointestinal tract submucosal tumorHumansMedicineStomach UlcerCandida albicansGastrointestinal tractHematologybiologybusiness.industryStomachCandidiasisGeneral MedicineMiddle Agedbiology.organism_classificationmedicine.diseaseSettore MED/18 - Chirurgia Generalemedicine.anatomical_structureDiabetes Mellitus Type 2CyclosporineFemaleItraconazolebusinessdescription
The gastrointestinal tract of healthy individuals is colonized by hundreds of saprophytes and mycetes, especially the Candida species, are habitual ones. Under certain conditions, the fungal flora may overgrow, resulting in lesions of the digestive mucosa which, rarely, can have a local diffusion and/or spread to the lympho-hematogenous system. Mycotic infections of the stomach can sometimes look like benign gastric ulcers. Here, we present the case report of a woman, aged 64, who presented with type II diabetes mellitus and psoriasis, on chronic treatment with cyclosporin A and with endoscopic evidence of an ulcerated, vegetating gastric lesion secondary to Candida albicans infection. Although strongly suggestive of malignancy, it completely healed after cyclosporin withdrawal and the administration of oral antifungal drugs.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-09-01 |