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RESEARCH PRODUCT
Solitary Fibrous Tumor of the Lower Leg: A Rare and Difficult Diagnosis
Francesco MoschellaLuigi MontesanoAdriana CordovaMatteo RossiAda Maria FlorenaSalvatore D'arpasubject
Pathologymedicine.medical_specialtySolitary fibrous tumorbiologybusiness.industryCD99CD34VimentinCase Reportmedicine.diseaseIncreased riskSolitary Fibrous Tumorbiology.proteinMedicine and Health SciencesMedicineNeoplasmSurgerySignificant riskDifferential diagnosisbusinessdescription
Summary: Solitary fibrous tumor (SFT) is a rare neoplasm that commonly originates in the pleura. Extrapleural locations are rare and for this reason sometimes difficult to diagnose. Malignant forms with local recurrence or distant metastases have been reported, also as a consequence of inappropriate treatment. In this article, we report the case of an SFT of the lower leg in a 37-year-old man. Leg SFT is a rare occurrence, and differential diagnosis may be difficult because they can mimic a variety of benign and malignant mesenchymal tumors; immunohistochemical analysis for CD34, CD99, vimentin, and Bcl-2 is necessary. Misdiagnosis carries a significant risk of inadequate removal with subsequent increased risk of recurrence and distant metastases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-10-01 | Plastic and Reconstructive Surgery Global Open |