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RESEARCH PRODUCT
Peroxisomes: biochemistry, molecular biology and genetic diseases— a video programme for teaching students
Norbert LatruffeShawn J. Hassellsubject
Computer analysisBiochemistryRat liverPeroxisome ProliferationBiologyPeroxisomeBiochemistrydescription
Abstract Peroxisome proliferation in rodent liver is a good biochemical marker of toxicology for several classes of xenobiotics, including fibrates; phthalates and adipates; or chlorophenoxy-acetate, a herbicide. Research in peroxisomes provides a good example of the integration of fields related to basic sciences and biomedical and industrial health. A 25 min video programme illustrates techniques involved in the characterization of purified peroxisomes ( Fig. 1 Download high-res image (70KB) Download full-size image Fig. 1 . Electron microscope view of isolated peroxisomes (from rat liver ×50 000). ) and membranes, immunoblotting, measurement of proliferation markers, mRNA analysis at the post-transcriptional level, DNA techniques, cell cultures as biological models and computer analysis. It is aimed at undergraduates and non-biochemist advanced students in biology.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2000-05-01 | Biochemical Education |