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RESEARCH PRODUCT
Relationship between maximal fat oxidation and oxygen uptake: comparison between type 2 diabetes patients and healthy sedentary subjects
Dario CerasolaGiuseppe RussoDanila Di MajoAngelo CataldoMarco GiammancoMarcello Trainasubject
medicine.medical_specialtyendocrine system diseasesChemistryBiochemistry (medical)nutritional and metabolic diseasesPlant ScienceType 2 diabetesmedicine.diseaseOxygen uptakeGeneral Biochemistry Genetics and Molecular Biologymetabolism fat oxidation rate oxygen uptake exercise diabetesEndocrinologyFat oxidation ratelcsh:Biology (General)Fat oxidationDiabetes mellitusInternal medicinemedicineOxidative capacityAerobic exerciseGraded exercise testlcsh:QH301-705.5human activitiesdescription
The contribution of fat oxidation to energy production during exercise is influenced by intensity of exercise. The aim of this study was to assess the relationship between the highest value of fat oxidation rate (FATmax) and the oxygen uptake (VO2) in sedentary type 2 diabetes (T2D) patients vs healthy sedentary subjects. Sedentary T2D patients and healthy sedentary subjects were evaluated to a graded exercise test, and oxygen uptake and fat oxidation rate were detected. Data show that in T2D patients fat oxidation rate is not impaired and the positive linear correlation between FATmax and both VO2 and VO2max suggests that even in T2D patients the muscle oxidative capacity might increase in response to aerobic training.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2014-01-10 | Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale |