6533b85ffe1ef96bd12c1373

RESEARCH PRODUCT

Osteogenesis imperfecta and hyperplastic callus formation: light- and electron-microscopic findings.

H. StössA. KarbowskiRolf E. BrennerU. VetterJürgen W. SprangerBertram F. Pontz

subject

HyperplasiaCallus formationChemistryfungifood and beveragesAnatomyHyperplasiaOsteogenesis Imperfectamusculoskeletal systemmedicine.diseaseOsteochondrodysplasialaw.inventionbody regionsMicroscopy Electronsurgical procedures operativeOsteogenesis imperfectalawCallusmedicineHyperplastic callus formationHumansElectron microscopeBony CallusElectron microscopicGenetics (clinical)

description

In rare cases of osteogenesis imperfecta, an "overshoot" growth of new bone may occur, which, clinically gives the impression of a tumour. This condition is known as hyperplastic callus formation. Morphology showed an excessive mixed desmal-chondral osteoneogenesis. Atypical collagen fibrils in non-callus tissue represent an indicator for this callus formation in individual patients.

10.1002/ajmg.1320450222https://pubmed.ncbi.nlm.nih.gov/8456814