6533b85ffe1ef96bd12c1d69
RESEARCH PRODUCT
Combined therapy with acyclovir and adenosine arabinoside in herpes simplex encephalitis.
Hans Christian HopfAxel RambowGünter KrämerRoland Bessersubject
Adultmedicine.medical_treatmentAcyclovirmedicineHumansAciclovirVidarabineComaChemotherapybusiness.industryHerpes Simplexmedicine.diseaseVirologyAdenosineHemiparesisNeurologyEncephalitisDrug Therapy CombinationFemaleNeurology (clinical)Viral diseasemedicine.symptombusinessTomography X-Ray ComputedEncephalitisVidarabinemedicine.drugdescription
We report a case of herpes simplex encephalitis (HSE) with initial coma and severe left-sided hemiparesis in which combined treatment with adenine arabinoside and acyclovir was followed by complete recovery. This favorable result is discussed in view of the literature of HSE treatment including experimental studies on antiviral activity of both drugs. Combined treatment may be useful in severe cases of HSE.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1987-01-01 | European neurology |