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RESEARCH PRODUCT
Synthesis, characterization and X-ray crystal structures of cyclam derivatives. 7. Hydrogen-bond induced allosteric effects and protonation cooperativity in a macrotricyclic bisdioxocyclam receptor
Stéphane BrandèsMichel MeyerRoger GuilardLaurent FrémondGuy Yves VollmerEnrique Espinosasubject
ChemistryHydrogen bondStereochemistryAllosteric regulationX-rayCooperativityProtonationGeneral ChemistryCrystal structureCatalysisCharacterization (materials science)chemistry.chemical_compoundCyclamMaterials Chemistrydescription
The unprecedented cooperative protonation properties displayed by a barrel-shaped macrotricyclic tetraamine incorporating two 14-membered bisamide rings maintained in a face-to-face arrangement is rationalized in terms of allosteric effects upon binding of the first and third protons.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2005-01-01 | New Journal of Chemistry |