6533b85ffe1ef96bd12c25fb

RESEARCH PRODUCT

Impact of COVID-19 pandemic on acute heart failure admissions and mortality: a multicentre study (COV-HF-SIRIO 6 study)

Tomasz KulawikLeszek KamińskiJanusz ProkopczukKlaudyna GrzelakowskaMarcin GruchałaMichał KasprzakJacek KubicaPrzemysław PodhajskiAnna Tomaszuk-kazberukAldona KubicaOliwia BrychtMarcin MindykowskiPiotr JankowskiPaweł GrzelakowskiAndrzej KleinrokEliano Pio NavareseAgnieszka TycińskaMarek KozińskiMaciej LesiakStanisław BartuśAndrzej WesterMałgorzata OstrowskaSergiusz SowińskiJarosław KaźmierczakPiotr AdamskiMiłosz JaguszewskiMariusz GąsiorJacek KryśAgnieszka PawlakAgnieszka PawlakSebastian StankalaGleb MinczewJadwiga NesslerGrzegorz SkoniecznyBożena SobkowiczPaweł KrólMarcin KostkiewiczPaweł SzymańskiEdyta Anielska-michalakJacek LegutkoAndrzej CurzytekPrzemysław LeszekAndrzej BudajWioleta StolarekAneta DudekPrzemysław WilczewskiJarosław DrożdżLeszek GromadzińskiTomasz ZdrojewskiPrzemysław Mitkowski

subject

medicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Heart failureMedical careLevodopaCOVID‐19Internal medicinePandemicmedicineHumansDiseases of the circulatory (Cardiovascular) systemIn patientPandemicsRetrospective StudiesSARS-CoV-2business.industryMortality rateCarbidopaCOVID-19Original Articlesmedicine.diseaseIn‐hospital mortalityHospitalizationDrug CombinationsIn-hospital mortalityRC666-701Heart failureConcomitantAcute DiseaseOriginal ArticleCardiology and Cardiovascular MedicinebusinessHospital stay

description

Abstract Aims The coronavirus disease‐2019 (COVID‐19) pandemic has changed the landscape of medical care delivery worldwide. We aimed to assess the influence of COVID‐19 pandemic on hospital admissions and in‐hospital mortality rate in patients with acute heart failure (AHF) in a retrospective, multicentre study. Methods and results From 1 January 2019 to 31 December 2020, a total of 101 433 patients were hospitalized in 24 Cardiology Departments in Poland. The number of patients admitted due to AHF decreased by 23.4% from 9853 in 2019 to 7546 in 2020 (P < 0.001). We noted a significant reduction of self‐referrals in the times of COVID‐19 pandemic accounting 27.8% (P < 0.001), with increased number of AHF patients brought by an ambulance by 15.9% (P < 0.001). The length of hospital stay was overall similar (7.7 ± 2.8 vs. 8.2 ± 3.7 days; P = not significant). The in‐hospital all‐cause mortality in AHF patients was 444 (5.2%) in 2019 vs. 406 (6.5%) in 2020 (P < 0.001). A total number of AHF patients with concomitant COVID‐19 was 239 (3.2% of AHF patients hospitalized in 2020). The rate of in‐hospital deaths in AHF patients with COVID‐19 was extremely high accounting 31.4%, reaching up to 44.1% in the peak of the pandemic in November 2020. Conclusions Our study indicates that the COVID‐19 pandemic led to (i) reduced hospital admissions for AHF; (ii) decreased number of self‐referred AHF patients and increased number of AHF patients brought by an ambulance; and (iii) increased in‐hospital mortality for AHF with very high mortality rate for concomitant AHF and COVID‐19.

10.1002/ehf2.13680https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.13680