6533b860fe1ef96bd12c2f01
RESEARCH PRODUCT
Cyclecondensation of 3-amino-1,2,4-triazole with substituted methyl cinnamates
Herbert MeierOleg V. ShishkinSergey M. DesenkoV. D. OrlovVictoria V. LipsonSergey A. KomykhovV. P. KuznetsovE. E. Lakinsubject
chemistry.chemical_compoundchemistryOrganic ChemistryCinnamates3-Amino-124-triazoleCarbon-13 NMRMedicinal chemistrydescription
The reaction of 3-amino-1,2,4-triazole (1) with substituted methyl cinnamates 2a-h leads selectively to the formation of 7-aryl-6,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones 3a-h. The structure eluci dation of the products is based on ir, 1H and 13C nmr measurements and X-ray diffraction.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-01-01 | Journal of Heterocyclic Chemistry |