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RESEARCH PRODUCT
Pigmented Squamous Cell Carcinoma In Situ: Report of a New Case and Review of the Literature
Florence Zumbaio MistroMichelle PalmieriSergio KignelFabiana MartinsPaulo Henrique Braz-silvaDo Canto Amsubject
In situIncisional biopsyPathologymedicine.medical_specialtyOral Medicine and Pathologybusiness.industryMelanomaCase Reportmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Lesion030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinomamedicineImmunohistochemistryBasal cellDifferential diagnosismedicine.symptombusinessGeneral Dentistrydescription
Pigmented squamous cell carcinoma in situ (PSCCIS) is very rare, being clinically described as a pigmented lesion with histological characteristics of an in-situ carcinoma presenting pigmentation within neoplastic cells. A 50-year-old Afro-descendant man came for clinical evaluation of a painful black and red lesion located on the right aspect of the oropharyngeal isthmus. After incisional biopsy, the resulting sample was described as a pigmented squamous cell carcinoma in situ, a diagnosis further confirmed by immunohistochemical analysis. Treatment consisted in total excision of the lesion, and no recurrence was observed after a 30-month follow-up. Clinicians and pathologists should be aware of PSCCIS as a differential diagnosis of melanoma, a lesion which significantly increases the morbidity and mortality rates among these patients. Key words:Pigmented squamous cell carcinoma in situ; oropharyngeal mucosa; immunohistochemistry.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-11-01 | Journal of Clinical and Experimental Dentistry |