6533b860fe1ef96bd12c3053

RESEARCH PRODUCT

Use of multiple polygenic risk scores for distinguishing schizophrenia-spectrum disorder and affective psychosis categories in a first-episode sample; the EU-GEI study

Victoria RodriguezLuis AlamedaDiego QuattroneGiada TripoliCharlotte Gayer-andersonEdoardo SpinazzolaGiulia TrottaHannah E. JongsmaSimona Stilo La Cascia CaterinaLaura FerraroDaniele La BarberaAntonio LasalviaSarah TosatoIlaria TarriconeElena BonoraStéphane JamainJean-paul SeltenEva VelthorstLieuwe De HaanPierre-michel LlorcaManuel ArrojoJulio BobesMiguel BernardoCelso ArangoJames B. KirkbridePeter B. JonesBart P. RuttenAlexander RichardsPak C. ShamMichael O'donovanJim Van OsCraig MorganMarta Di FortiRobin M. MurrayEvangelos Vassos

subject

bipolar disorderAffective psychosisdiagnosisGENETIC-RELATIONSHIPSschizophrenia-spectrum disorderPsychiatry and Mental healthAffective psychosis bipolar disorder diagnosis genetics polygenic score psychosis psychotic depression schizophrenia-spectrum disorderLIABILITYpsychotic depressiongeneticspolygenic scorepsychosisGENOME-WIDE ASSOCIATIONApplied Psychology

description

This work was supported by funding from the European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (Project EU-GEI). (...) CA was supported by the Spanish Ministry of Science and Innovation; Instituto de Salud Carlos III (SAM16PE07CP1, PI16/02012, PI19/024), co-financed by ERDF Funds from the European Commission, ‘A way of making Europe’, CIBERSAM. Madrid Regional Government (B2017/BMD-3740 AGES-CM-2), Fundación Familia Alonso and Fundación Alicia Koplowitz. MB was supported by the Ministry of Economy and Competitivity (PI08/0208; PI11/00325; PI14/00612), Instituto de Salud Carlos III – ERDF Funds from the European Commission, ‘A way of making Europe’, CIBERSAM, by the CERCA Programme/Generalitat de Catalunya and Secretaria d’Universitats i Recerca del Departament d’Economia I Coneixement (2017SGR1355). Departament de Salut de la Generalitat de Catalunya, en la convocatoria corresponent a l’any 2017 de concessió de subvencions del PERIS 2016-2020, modalitat Projectes de recerca orientats a l’atenció primària, amb el codi d’expedient SLT006/17/00345; and grateful for the support of the Institut de Neurociències, Universitat de Barcelona.

10.1017/s0033291721005456https://doi.org/10.1017/s0033291721005456