6533b860fe1ef96bd12c3091
RESEARCH PRODUCT
Cluster analysis of clinical data reveals three pediatric eosinophilic gastrointestinal disorder phenotypes
Gian Luigi MarsegliaMartina VottoGiovanna CilluffoStefania La GruttaSalvatore FasolaAmelia LicariGiuliana Ferrantesubject
ImmunologyphenotypesCluster analysis eosinophilic gastrointestinal disorder children phenotypesEnteritisEGIDs cluster analysisPhenotypepediatricCluster analysiseosinophilic gastrointestinal disorderchildrenGastritisEosinophiliaPediatrics Perinatology and Child HealthHumansImmunology and AllergyChilddescription
Primary eosinophilic gastrointestinal disorders (EGIDs) are a spectrum of emerging inflammatory diseases, which may involve any part of the gastrointestinal (GI) tract and lead to a pathological eosinophilic mucosal infiltration.1,2 Based on the anatomical site of the eosinophil inflammation, EGIDs are classified into eosinophilic esophagitis (EoE) and nonesophageal EGIDs.This study aimed to characterize EGIDs heterogeneity by performing cluster analysis on a cohort of children and adolescents followed at the Pediatric Center for Eosinophilic Gastrointestinal Disorders (CPED) in Pavia, Italy, using an extensive pediatric primary care database from our University Hospital
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-01-01 |