6533b860fe1ef96bd12c3187

RESEARCH PRODUCT

Habituation or lack of habituation: What is really lacking in migraine?

Giuseppe CosentinoFilippo BrighinaBrigida Fierro

subject

Malemedicine.medical_specialtyNeurologyPhotic StimulationMigraine DisordersSensory systemMigraine Disorders050105 experimental psychology03 medical and health sciences0302 clinical medicineMigraine DisorderPhysiology (medical)medicineHumans0501 psychology and cognitive sciencesHabituationHabituation Psychophysiologicbusiness.industry05 social sciencesmedicine.diseaseSensory SystemsMigraineNeurologyEvoked Potentials VisualFemaleNeurology (clinical)businessSensory SystemNeuroscience030217 neurology & neurosurgeryPhotic StimulationHuman

description

Migraine is very prevalent disease with consistent disability and socioeconomic burden (Lipton et al., 2007). Despite intensive research effort, particularly in last decades, allowing significant insight in many aspects of the disease, its precise pathophysiological bases remain still to be defined. One influential view suggests that dysfunctions in sensory information processing could play a critical role (de Tommaso et al., 2014). In this frame a relevant phenomenological marker is considered the inability of migraine patients to habituate to repeated sensory stimulation.

10.1016/j.clinph.2015.05.028http://hdl.handle.net/10447/249773