6533b860fe1ef96bd12c31c6
RESEARCH PRODUCT
Intramolecular Michael reaction of tert-butylsulfinyl ketimines: asymmetric synthesis of 3-substituted indanones.
Elsa RodríguezMiguel A. MaestroLidia HerreraSantos FusteroAmparo AsensioPablo Barriosubject
Ortho positionMolecular StructureStereochemistryChemistryOrganic ChemistryEnantioselective synthesisStereoisomerismBiochemistryMedicinal chemistryIntramolecular forceIndansNitrilesMichael reactionIminesPhysical and Theoretical ChemistryConjugatedescription
Aromatic tert-butylsulfinyl ketimines bearing a suitable Michael acceptor at the ortho position readily undergo an intramolecular conjugate addition achieving indanone derivatives in good yields and complete diastereoselectivity.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 | Organic letters |