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RESEARCH PRODUCT
Heterocyclic rearrangements.N,N-diphenylhydrazones, oximes andO-methyloximes of 3-benzoyl-5-phenyl-1,2,4-oxadiazole
Nicolò VivonaSilvestre BuscemiMichele RucciaVincenzo Frennasubject
chemistry.chemical_classificationchemistry.chemical_compoundIndazoleSemicarbazideBicyclic moleculeChemistryOrganic ChemistryOrganic chemistryOxadiazoleHydrazoneBenzeneMedicinal chemistrydescription
The behaviour of (E)- and (Z)-N,N-diphenylhydrazones and O-Methyloximes of 3-benzoyl-5-phenyl-1,2,4-oxadiazole has been studied. When refluxed in benzene, or in dioxane-water (1:1), the (Z)-N,N-diphenylhydrazone 8Z gave the indazole 11 or the substituted semicarbazide 12, respectively. The O-methyloxime 14Z did not give any rearrangement. A criticism of the oximation reaction of 3-benzoyl-5-phenyl-1,2,4-oxadiazole is also reported.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1985-01-01 | Journal of Heterocyclic Chemistry |